Researcher's Profile

LI-KAI TSAI (蔡力凱)

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  • Cerebrovascular disease, neurogenetics
  • Neurology (神經科/部)
  • Clinical Associate Professor (臨床副教授)

Research Outline      2014-10-27 11:00:36

My lab is primarily focused on studies of the therapy for spinal muscular atrophy (SMA). While SMN acts to modulate and correct the neuromuscular junction for functional improvement, SMN-independent targets could play a role of extension in the survival of motor neurons and reduce the influence of SMN depletion in axonal dynamics. We used the SMA-like mouse model and cell lines to investigate the effects of different SMN-dependent and SMN-independent therapy for future SMA treatment.